fasting scientific resources
Unlocking the Benefits of Fasting
Nature Cell Biology: Autophagy and Longevity
This study reveals how intermittent fasting regulates aging by activating autophagy, a process essential for cellular maintenance and longevity. It shows that autophagy through spermidine extends lifespan across organisms.Read on Nature Cell Biology Phys.org
Fasting: Molecular Mechanisms and Clinical Applications
This comprehensive study reviews how fasting triggers autophagy, aiding in cellular detox and regeneration. The focus is on fasting's impact on metabolism and disease prevention.eClinical Medicine: Fasting and Cardiovascular Health
Harvard’s meta-analysis in eClinical Medicine indicates that intermittent fasting reduces risk factors like LDL cholesterol, triglycerides, and systolic blood pressure, underscoring fasting’s benefits for heart health.View at Harvard Health Harvard Health
MIT Research on Stem Cell Regeneration Post-Fasting
This MIT study highlights fasting’s role in stimulating stem cell proliferation after refeeding, aiding cellular repair and potentially improving resilience to intestinal injuries.Intermittent Fasting and Human Metabolic Health
This review analyzes the effects of prolonged fasting on metabolism, emphasizing enhanced immune response and cellular repair mechanisms through controlled fasting protocols.
Mindfulness + Emotional Well-being
“Spermidine is Essential for Fasting-Mediated Autophagy and Longevity”
This study examines how fasting initiates autophagy, an essential cellular process associated with stress resilience, cognitive clarity, and extended longevity. The study highlights the broader effects of fasting on emotional and mental health through cellular rejuvenation.Read on Nature Cell Biology Phys.org
“Does the Wim Hof Method Improve Physiological and Psychological Outcomes?”
This study assesses the Wim Hof Method’s impact on physiological and psychological health, particularly through its effects on the stress response, anti-inflammatory markers, and emotional resilience. It provides scientific evidence for the method's potential in enhancing mental clarity, focus, and emotional regulation, relevant to mindfulness and well-being practices."Intermittent Fasting as a Potential Therapeutic Instrument for Major Depression Disorder: A Systematic Review of Clinical and Preclinical Studies" – International Journal of Molecular Sciences (MDPI)
This review explores the effects of intermittent fasting (IF) on mood and neurochemistry, specifically focusing on its impact on depression. The research suggests that IF may improve mood through neurochemical and circadian regulatory effects, though more targeted studies are needed to solidify findings."Intermittent Fasting and Mental Health Benefits" – National Institute on Aging (NIA) Summary of Findings in NEJM
A comprehensive review by NIA researchers, published in The New England Journal of Medicine, discusses how intermittent fasting can improve mood, resilience, and cognitive function through metabolic switching and neuroprotective ketone production. This adaptive response is linked to enhanced mental clarity and emotional regulation, making it a valuable resource for understanding the mental health benefits of fasting."The Effects of Intermittent Fasting on Brain and Cognitive Function" – Nutrition Reviews (Oxford Academic)
This study reviews intermittent fasting’s impact on cognitive health and emotional well-being, focusing on benefits like increased brain-derived neurotrophic factor (BDNF), which supports neuroplasticity and mood regulation. It provides a robust scientific overview of fasting’s effects on mental and cognitive resilience.
Supplement Support for Optimal Health
“Thorne PolyResveratrol-SR for Healthy Aging and Inflammatory Response” – Mayo Clinic
This article from Mayo Clinic discusses the health benefits of Thorne's PolyResveratrol-SR, which combines trans-resveratrol with pterostilbene, curcumin, and green tea phytosome. This formula is specifically designed to support a normal inflammatory response, reduce oxidative stress, and promote healthy aging. Trans-resveratrol and pterostilbene enhance metabolic functions and cardiovascular health, which can be particularly beneficial during fasting by supporting cellular protection and longevity.“Anemia of Chronic Disease: Treatment with Lipoic Acid, Resveratrol, & Curcumin” – Naturopathic Doctor News and Review (NDNR)
NDNR reviews the combined effects of curcumin, resveratrol, and alpha-lipoic acid in reducing oxidative stress markers and inflammatory cytokines. This combination may support the immune system, reduce inflammation, and protect cellular health. Curcumin and alpha-lipoic acid, in particular, offer enhanced antioxidant effects that are helpful during fasting, as they aid in detoxification and cellular repair, essential for individuals seeking sustained metabolic health.“Alpha-Lipoic Acid, Acetyl-L-Carnitine, and Cognitive Health” – Life Extension
Life Extension provides insights into how alpha-lipoic acid (ALA) and acetyl-L-carnitine support mitochondrial function, combat oxidative damage, and protect cognitive health. ALA’s antioxidant properties are particularly beneficial for individuals practicing fasting, as it enhances energy metabolism and helps neutralize free radicals. This combination supports mental clarity and energy, making it a valuable addition to fasting routines.“Trans-Resveratrol and Longevity: Benefits for Inflammation and Antioxidant Support” – ProHealth
This ProHealth article examines trans-resveratrol's bioavailability and its significant anti-inflammatory, antioxidant, and cardiovascular benefits. Trans-resveratrol works in tandem with curcumin to reduce systemic inflammation and protect brain and cardiovascular health, making it ideal for long-term fasting regimens aimed at cellular health. The longevity-promoting properties of trans-resveratrol, especially in the active liposomal form, provide enhanced bioavailability for maximum absorption.“Research on Intermittent Fasting and Health Benefits” – National Institute on Aging (NIA)
Published by the NIA, this comprehensive review highlights the broader health benefits of intermittent fasting, including increased stress resistance, improved glucose regulation, and reduced inflammation. The study references essential compounds such as MCT oil and coconut oil, which can help sustain energy levels during fasting by providing alternative fuel sources. This research supports the idea that fasting, when combined with high-quality supplements, can significantly bolster metabolic health.